sterile equipment

Sterility Isolators

The pharmacopoeias require sterility testing of sterile pharmaceutical products to determine the acceptability of a production batch. It is a fundamental element in the validation of sterilization and should be carried out in such a way as to avoid the risks of false positive and false negative results.


Telstar’s range of rigid wall sterility testing equipment is designed to avoid this risk and protect the product from externally generated factors and the process that could compromise its quality.

The correct ergonomic design of the unit is combined with a sound plan for manufacturing that uses the latest technologies, ensuring easy installation and efficient inspection and testing.

The insulation equipment complies with the ISO 14644-7: 2004 standard, generating an EU-grade BPM environment in the entire chamber. Also, it has optional equipment that the client can select to meet.

bioburden testingFalse positive results are usually due to laboratory contamination due to the technician/technique’s test or error environment, and generate additional work regarding additional documentation required, and add significant cost as it delays or prevents the release of a product for its sale. The Telstar sterility insulator has been developed to cover a wide variety of customer needs. The ability of the units to provide a reliable aseptic environment for testing for sterility and other aseptic processes is unquestionable.

A minimum reduction of 6 logarithms in microorganisms of spore formation is achieved and validated consistently with a challenge test of biological indicators. The range of Telstar sterility test isolation equipment is suitable for sterility testing of both direct injection and filter membrane with the flexibility of being able to decontaminate with different types of available decontamination systems.

sterility test for parenterals rabs isolator

Symptom

barrier isolator hood The first sign of impotence in the couple is having sexual intercourse without using contraception for a year and not getting pregnant. In case this happens, you should go to a fertility specialist to do a series of tests to both members of the couple.

As for female sterility, this usually does not manifest itself in any way, so the woman will not notice any symptoms and will not be aware of the problem until she goes to a gynecological review or consultation for fertility problems. However, sometimes there may be discomfort or signs that make the doctor suspect pathology, such as pain, discomfort, menstrual changes and even fever. In case of any trouble or sign of alteration, a doctor should be consulted, but it is essential that the woman goes to periodic gynecological exams to guarantee her health and well-being.

Female Sterility: Symptoms, Causes, And Treatment

infertility Female sterility is the woman’s inability to conceive. It can be due to multiple reasons, so it is necessary to do a fertility study to determine the treatment to follow. Usually, there are no symptoms, and the woman is unaware of the problem until she goes to the doctor for not achieving a pregnancy.

Although sterility and infertility are used colloquially as synonyms, it is essential to keep in mind that they are not. A sterile woman cannot have a pregnancy because fertilization or implantation is not possible, whereas an infertile woman is one who can have a pregnancy, but it does not come to term. We recommend that you visit this link for more information: Sterility and infertility, what are the differences?

Types

infertility The problems of sterility can be of different types. Thus, depending on whether or not there is a possibility of cure or treatment, we find:

Sterility Absolute Or Permanent: Fertilization or implantation are disabled. There is no possibility of surgery, regression or spontaneous healing.

Relative Sterility: there is some factor that can decrease female fertility. This can disappear spontaneously, or treatment is available. On the other hand, if the woman has previously achieved pregnancy or not, two different types can be distinguished:

fertility Primary Sterility: pregnancy has never been made.

Secondary Infertility: pregnancy is not completed but there has been a previous one. Also, we can distinguish between involuntary and voluntary sterility:

Sterility Voluntary: usually also known as sterility or surgical tubal ligation. It is the one voluntarily used by women to plan a family.male infertility

Involuntary Infertility: appears naturally, without medical intervention. In these cases, the woman does not manage to have offspring. In this article, we will talk about involuntary infertility.

For What Is This?

The main reasons why a woman has fertility problems are the following:

  • Hormonal and ovulation issues Problems in the cervix or cervix
  • Tubal alterations
  • Uterine alterations

Female infertility can appear due to one of these alterations or a combination of several. Currently, the most frequent cause of female infertility is advanced maternal age. Over 35-37 years, both the quantity and the quality of the ovules ( ovarian reserve ) is meager, and therefore the possibility of pregnancy is drastically reduced, especially after 40.

fertility hormones

Hormonal And Ovulation Problems

hormonal imbalanceThe hormones that are responsible for the normal functioning of the ovary are GnRH (human chronic namedropping), FSH (folio-stimulating hormone), LH (routinizing hormone), progesterone and radiologist.

Any alteration in any of these hormones that control the ovarian cycle of the woman can lead to a failure in the maturation of the ovules or problems of ovulation. In case the hormonal problem persists in time, that is, it is not a specific alteration; it can lead to female sterility.

hormonal imbalance treatmentWhen the menstrual cycle is altered, ovulation problems are usually associated with alterations in menstruation or gonorrhea (absence of menstruation). This causes the woman to suspect that there is a problem with her rule and come to consultation. However, some pathology, such as hidden ovarian failure, appears without associated menstrual issues.

Among the factors that can cause alterations in ovulation are:

  • Stress
  • Problems with the thyroid gland
  • Treatments for cancer (radiotherapy or chemotherapy)
  • Some types of medication
  • Environmental factors

Modifications In The Weight Of Women, Whether Obesity Or Anorexia.

Cervical Problems

when is a woman fertile The cervix is the anatomical structure that connects the vagina to the uterus, so the sperm must be able to cross it on its way to the ovule. If there is any abnormal formation, such as polyps or myomas, the duct may be blocked, and they may have difficulty passing through it.

It is also essential that the cervical mucus has the proper structure and consistency, as it serves as a selection barrier that only allows the passage of the best sperm. It should be elastic and slippery, similar to egg white.

On the other hand, bacteria and pathogenic microorganisms can cause infections, pH changes and inflammation, which can prevent the rise of sperm.

Alterations In The Fallopian Tubes

can hormonal imbalance cause infertility In the Fallopian tubes is where fertilization occurs, so it is essential that they have an adequate structure and that they are permeable, that is, they allow fluid to pass through, so that the sperm can reach the egg and, a Once fertilized, the embryo can travel to the uterus.

For a natural pregnancy to occur, it is imperative that at least one of the two tubes be permeable. If both machines are obstructed, the woman will be sterile.

The problems in the tubes can be due to infections, endometriosis, malformations, pelvic inflammatory disease (PID), salinity or hydroponically, among others.causes of infertility